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pentobarbital will reduce the extent or impact of nilotinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will lower the extent or outcome of lapatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.The usage of barbiturates to be a rest-inducing drug is at pres